Cell Membrane Therapy: Clinical Practice in Brain, Liver and Cardiovascular Diseases

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Cell Membrane Therapy: Clinical Practice in Brain, Liver and Cardiovascular Diseases


A book by Prof. Dr. Mike Chan and Prof. Dr. Yuriy Nalapko
Published by Matador, Troubador.co.uk, London – Medical Research: ISBN 978 1838592 509

SKU: ISBN978-1-83859-250-9 Category:
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A book by Prof. Dr. Mike Chan and Prof. Dr. Yuriy Nalapko
Published by Matador, Troubador.co.uk, London – Medical Research: ISBN 978 1838592 509

Human Cell Membrane Therapy explores the theoretical and practical dimensions of improving service provision on majority of the diseases caused by cell damage. This readable and well-structured book is based on the reviews of current scientific publications on cellular membranes, its chemical structure and changes in many diseases. This monograph opens the new overview of the concepts of cell membranes therapy.

Detailed role of phosphatidylcholine as the principal component of the cell membranes is described. Among the important issues discussed are Parkinson’s and Alzheimer’s diseases, atherosclerosis, fatty liver disease, diabetes mellitus etc. The final chapter evaluated progress in the use of PlaqX – phosphatidylcholine-based substance, which is able to restore the cell membranes and provide significant health improvement. This detailed review and authors experience will be of value to anyone with an interest in the area of regenerative, biomolecular, and anti-aging medicine.

Professor Dato’ Sri Dr. Mike KS Chan is one of the pioneers of cellular and cell membrane therapy in Europe and Asia since the early 1980’s. He founded and spearheaded one of the world’s largest researches for bio-molecular medicine based in Switzerland and Germany with presence in almost 80 countries globally. He conducted more than 1,000 lectures, seminars and symposiums worldwide across more than 60 countries in the field of anti-aging, cell regeneration, regenerative medicine and stem cell therapies.

Dr. Yuriy Nalapko is academician and practical doctor in anesthesiology and intensive care. One of the areas of his scientific interests is longevity and a cell functioning in different diseases. His Philosophy Degree dissertation was devoted to the intensive care of brain injury patients. Last time he pays his attention to the cell membranes and the different methods of its structural and functional corrections. He considers the cell membrane therapy as the important component of the regenerative medicine and biomolecular therapy.

Table of Content

Foreword xi
Preface xii
Abbreviations xv
From Cell to Molecule 1
1.1.Cellular membrane and its structure 1
1.2. Essential phospholipids 2
Chemical structure and types of phospholipids 2
Cholesterol 4
Choline 4
Acetylcholine 5
CDP-choline 5
1.3. Biosynthesis of phospholipids 6
Phosphatidylcholine 6
Phosphatidylethanolamine 7
Sphingomyelin (SM) 7
Phosphatidylcholine in a Healthy Body 8
2.1. Central nervous system 8
2.2. Cardiovascular system. Atherosclerosis and inflammation 10
Autoimmunity and cholesterol homeostasis 13
2.3. Immune system 14
Phospholipids and immune cell proliferation and migration 14
Infections can stimulate atherosclerosis 15
Targeting cholesterol and inflammation 16
Anti-inflammatory effect of phosphatidylcholine 16
Phosphatidylcholine: From Nature to Medicine 19
3.1. Manufacturing 19
3.2. Natural sources of phosphatidylcholine 20
3.3. Non-medical functional properties of phosphatidylcholine 20
3.4. Brief history of phosphatidylcholine use in medicine 21
Essential phospholipids / polyenylphosphatidylcholine 23
Deoxycholine 24
Pharmacokinetics of exogenous phosphatidylcholine 24
Phosphatidylcholine at Clinical Practice 25
4.1. Neurodegenerative diseases 25 25
Alzheimer’s disease 25
Parkinson’s disease 27
4.2. Brain stroke and central nervous system injury 28
Traumatic brain injury 28
Spinal cord injury 30
4.3. Liver diseases and diabetes 30
Non-alcoholic fatty liver disease 31
Overview of reviewed clinical studies regarding the influence of administration of PC on FLD (by K-J Gundermann et al., 2016) 32
Alcoholic liver disease 36
Acute viral hepatitis 38
Chronic hepatitis 39
Cirrhosis of the liver and hepatic coma 40
Toxic liver damage 41
Diabetes 41
4.4. Atherosclerosis 42
4.5. Ophthalmology 43
4.5. Ophthalmology 43
Retinal degeneration 43
Amblyopia and non-arteritic ischemic optic neuropathy 44
Glaucoma 44
4.6. Infections 46
4.7. Acute respiratory distress syndrome 48
Practical Aspects of PlaqX 51
Indications for PlaqX therapy 54
Contraindications 55
Safety 55
Adverse drug reactions 56
Forms 56
Protocols 56
Drug interactions 57
Case Studies 57
Alchoholic Fatty Liver Disease 63
Summary 65
References 67

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