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GI-Proenzyme is a proteolytic enzyme supplement that may be beneficial in supporting immune responses!

GI-Proenzyme is a proteolytic enzyme supplement that may be beneficial in supporting immune responses!

It’s important to understand that no supplement, diet, or other lifestyle modification other than social distancing and proper hygiene practices can protect you from COVID-19. However, consuming nutritious foods, getting adequate sleep, rest, exercising and supplementing with certain supplements can improve immune responses.

MF3 GI-Proenzyme

The human body is capable to produces various types of metabolic enzymes that play a vital role in supporting the normal functions of the metabolic system.

However, the production of metabolic enzymes may decline as early as age 25 years old. Proteolytic enzymes are complex, and our body has a limited capacity and required a lot of energy and amino acid to synthesis these enzymes quickly. Without metabolic enzymes, we are more susceptible to diseases, and our bodies degenerate faster. Since our body is not making enough of it, supplementation of proteolytic is essential to help replace what has been lost due to age and other factors.

Proteolytic enzymes exert both digestive and systemic functions. A deficit of metabolic enzymes is the root of most chronic health problems.

  • Digestive System
    When taken with meals, proteolytic enzyme help to optimize the digestion, assimilation and absorption of nutrients from protein. A lack of digestive enzymes can lead to digestive and other health problems.
  • Systemic Functions
    Systemic enzymes, also called proteolytic enzymes, when taken on an empty stomach, proteolytic enzymes will pass through the intestine lining as active molecules enter the circulatory system and circulate throughout the body, it remains biologically active with a half-life of 6–9 hours.

GI-Proenzyme are designed to provide Systemic Enzyme Support that plays an important role in helping to maintain healthy digestive system, healthy immune system, promote normal inflammatory processes within the body and thereby help support and speed healing.

The effect of systemic enzymes on immune function mediated at the level of the intestine.  Proteolytic enzymes exert indirect effects on the immune system by neutralizing immune triggers and releasing amino acids and also interact directly with the immune cells on the surface of the gastrointestinal tract.

GI-Proenzyme delayed released capsule release the proteolytic enzymes in the small intestine. They are absorbed intact as functional systemic enzymes into circulation.

For maximum systemic benefit, take GI-Proenzyme on an empty stomach at least 30 minutes before meal OR 2 hours after the last meal, first thing in the morning and bedtime, 2 capsules per day with a glass of water.

Suitable for anyone suffering from leaky gut, bloating, indigestion, weak or compromised immune system, and for general health maintenance.

Once transported across the vesicles and into circulation, it immediately complex to bait region of alpha-2 macroglobulin, form a alpha-2-macroglobulin protease complexes.

Once protease activated alpha-macroglobulin complex enters the cells via LRP -1, they are actively absorbed by waiting leukocytes.

Leukocyte that is now equipped with Systemic Protease – defensive protein, travel to the site of inflammation.

As a defensive protein, protease is directed to the site of inflammation by the immune system. It uses it as a tool to protect cells, signal other cells, or to degrade unwanted or invasive proteins.

Contraindications

May interfere with prescription blood thinners. They can be taken in conjunction, but recommended to dose them about four hours apart. (Please also seek for a physician’s advice).

Not recommended for those who are allergic to pineapples and papayas, pregnant and breastfeeding mothers.

Reference

  1. Barth, H & guseo dr, Andras & Klein, Reinhild. (2005). In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans. European journal of medical research. 10. 325-31.
  2. Biziulevicius GA. Where do the immunostimulatory effects of oral proteolytic enzymes (‘systemic enzyme therapy’) come from? Microbial proteolysis as a possible starting point. Med Hypotheses 2006;67(6):1386-8.
  3. Castell JV, Friedrich G, Kuhn CS, et al. Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake. Am J Physiol 1997;273:139-46
  4. Engwerda CR, Andrew D, Ladhams A, Mynott TL. Bromelain modulates T cell and B cell immune responses in vitro and in vivo. Cellular Immunology. 2001;210(1):66–75. [PubMed] [Google Scholar]
  5. Gaspani L, Limiroli E, Ferrario P, Bianchi M. In vivo and in vitro effects of bromelain on PGE(2) and SP concentrations in the inflammatory exudate in rats. Pharmacology. 2002 May;65(2):83-6
  6. Hale LP, Greer PK, Sempowski GD. Bromelain treatment alters leukocyte expression of cell surface molecules involved in cellular adhesion and activation. Clin Immunol 2002;104(2):183-90.
  7. Hale LP, Haynes BF. Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation. J Immunol 1992;149(12):3809-16
  8. Lehmann PV. Immunomodulation by proteolytic enzymes. Nephrol Dial Transplant. 1996 Jun;11(6):952-5
  9. Rathnavelu, V., Alitheen, N. B., Sohila, S., Kanagesan, S., & Ramesh, R. (2016). Potential role of bromelain in clinical and therapeutic applications. Biomedical reports5(3), 283–288. https://doi.org/10.3892/br.2016.720

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